Last Upate: 11/10/08


Computational Biology Group at Stanford Genome Technology Center
and
Data Interpretation Core of the Glue Grant

 

The host response to trauma and burns is a collection of physiological and pathological processes that depend critically upon the regulation of the human innate immune system. The Glue Grant consortium utilize microarrays, high throughput proteomics, cell separation methods, and bioinformatics to improve our biological understanding of inflammatory response to injury.

The Data Interpretation Core (DIC) focuses on the integrative analysis of comprehensive genomic, proteomic, and clinical data generated by the program. The major functions of DIC include:

• support the development and quality control of Glue Grant protocols for cell separation, sample processing, microarray and mass spectrometry proteomics;
• data analysis of microarray, high throughput proteomics, and cell functional data, as well as their correlation with clinical trajectories of patients;
• development of statistical and bioinformatic algorithms and software tools for large scale translational studies.

 

Here are some brief examples of our projects:

Prediction of Patient Outcomes from Blood Leukocyte using Gene Profile after Injury

Knowledge-based Analysis of Cell Specific Genomic Response to Injury

Microarray Analysis Beyond Gene Expression

 

 

For detailed information about the group's projects, please contact Wenzhong Xiao at "wzxiao at stanford.edu"